These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: First obtaining of glass solutions and phase diagram of glucose with fully tunable anomeric concentration.
    Author: Dujardin N, Willart JF, Dudognon E, Danède F, Descamps M.
    Journal: J Pharm Sci; 2010 Mar; 99(3):1476-83. PubMed ID: 19739111.
    Abstract:
    In this article we show the possibility to form amorphous alpha-glucose/beta-glucose molecular alloys directly in the solid state by comilling crystalline alpha-glucose and crystalline beta-glucose. Contrary to the usual melt quenching process, milling does not induce any mutarotation so that alloys can be obtained for the whole range of anomeric concentration. This offers the unique possibility to explore the phase diagram of this binary system which appears to be a eutectic mixture. The structural and thermodynamic investigations have been performed by powder X-ray diffraction and differential scanning calorimetry.
    [Abstract] [Full Text] [Related] [New Search]