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Title: Synthesis and thermal denaturation studies of covalently linked DNA triplexes. Author: Okamoto I, Ito S, Ono T, Ono A. Journal: Nucleic Acids Symp Ser (Oxf); 2009; (53):165-6. PubMed ID: 19749312. Abstract: We report on the synthesis and thermal stability of small covalently linked DNA triplexes. These modified triplexes were found to contain covalently linked T-T pairs at the edges, and thermal denaturation studies revealed that the covalent linking efficiently stabilized triplex formation.[Abstract] [Full Text] [Related] [New Search]