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  • Title: Docking simulation of polyamines on a kissing-loop RNA dimer.
    Author: Imai M, Chikatsu D, Inomata E, Oshima T, Kawai G.
    Journal: Nucleic Acids Symp Ser (Oxf); 2009; (53):273-4. PubMed ID: 19749366.
    Abstract:
    Polyamines, especially branched polyamines such as tetrakis(3-aminopropyl)ammonium (Taa), stabilize the tertiary structure of RNA molecules. In this study, we examined the polyamine binding site of the HIV-1 dimerization initiation site (DIS) in the kissing-loop dimer by the docking simulation. It was found that Taa binds predominantly to the kissing loop interaction site of DIS.
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