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  • Title: Reactive oxygen species scavenging activities and inhibition on DNA oxidative damage of dimeric compounds from the oxidation of (-)-epigallocatechin-3-O-gallate.
    Author: Qi X.
    Journal: Fitoterapia; 2010 Apr; 81(3):205-9. PubMed ID: 19751808.
    Abstract:
    The dimeric catechins dehydrotheasinensin A (2) and theacitrin C (3) were prepared from the oxidation of (-)-epigallocatechin-3-O-gallate (EGCG, 1), and their antioxidant activity was investigated using a chemiluminescence (CL) method in vitro. Both compounds showed significant inhibitory effects on reactive oxygen species (O(2)(-), H(2)O(2) and *OH) and DNA oxidative damage, with 2 being more potent than 3 and EGCG itself.
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