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  • Title: Investigating agenesis of the corpus callosum using functional MRI: a study examining interhemispheric coordination of motor control.
    Author: Lum C, McAndrews MP, Holodny AI, McManus KA, Crawley A, Chakraborty S, Mikulis DJ.
    Journal: J Neuroimaging; 2011 Jan; 21(1):65-8. PubMed ID: 19758290.
    Abstract:
    We report fMRI findings in 3 asymptomatic cases of agenesis of the corpus callosum, the largest white matter bundle in the brain, which is responsible for interhemispheric transfer of information. Sensory information was presented to 1 hemisphere, and the patients had to generate a motor response governed by the contralateral hemisphere. Enhanced ipsilateral motor pathways have been suggested as a compensation method for people with agenesis of the corpus callosums; our functional magnetic resonance imaging data did not support this theory.
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