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Title: Role of somatostatin and its analogues in the pathogenesis and treatment of diabetes mellitus. Author: Gerich JE. Journal: Metabolism; 1990 Sep; 39(9 Suppl 2):52-4. PubMed ID: 1976221. Abstract: Somatostatin secreted by pancreatic D cells is a potent inhibitor of insulin, glucagon and growth hormone secretion, as well as other cells. The role of abnormal pancreatic D-cell function in diabetes mellitus is unclear. However, development of long-acting selective somatostatin analogs might prove useful in the treatment of diabetes.[Abstract] [Full Text] [Related] [New Search]