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  • Title: Locomotion in the pulmonate snail Melampus--II. Recovery after pedal ganglion excision.
    Author: Snyder KA, Moffett SB.
    Journal: Comp Biochem Physiol A Comp Physiol; 1990; 96(3):407-14. PubMed ID: 1976482.
    Abstract:
    1. When one pedal ganglion is removed, snails first crawl using the unoperated side of the foot, but in 4-8 weeks the operated side exhibits an anterior-to-posterior gradient of recovery. 2. A ganglion bud bridges the site of the missing ganglion and axons project from intact central ganglia into the foot. 3. Rhythmic activity in right and left pedal nerve pairs is correlated during locomotion in the regenerated snails. 4. The oscillator in the remaining pedal ganglion drives bilaterally coordinated activity. Regenerated projections from the cerebral ganglia through the bud to the remaining pedal ganglion suffice to initiate locomotion.
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