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  • Title: Assisted reproductive technologies to establish pregnancies in couples with an HIV-1-infected man.
    Author: van Leeuwen E, Repping S, Prins JM, Reiss P, van der Veen F.
    Journal: Neth J Med; 2009 Sep; 67(8):322-7. PubMed ID: 19767658.
    Abstract:
    For HIV -1-infected men and women the introduction of highly active antiretroviral therapy (HART) in 1996 led to a spectacular increase in life expectancy and quality of life. In Western society where HART is readily available, HIV -1 is now considered to be a chronic disease and as a consequence quality of life is an important aspect for men and women with HIV-1. Many of them express the desire to father or mother a child. Assisted reproductive technologies, including intrauterine insemination (IUI), in vitro fertilisation (IVF) and intracytoplasmatic sperm injection (ICSI) in combination with semen washing have been used to decrease the risk of HIV -1 transmission in HIV-1-infected discordant couples with an HIV-1-infected man. This article aims to summarise the current state of the art of assisted reproductive technologies for couples with an HIV -1-infected man and to discuss current trends and dilemmas in the treatment of these couples.
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