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  • Title: Aaptamine alkaloids from the Vietnamese sponge Aaptos sp.
    Author: Shubina LK, Kalinovsky AI, Fedorov SN, Radchenko OS, Denisenko VA, Dmitrenok PS, Dyshlovoy SA, Krasokhin VB, Stonik VA.
    Journal: Nat Prod Commun; 2009 Aug; 4(8):1085-8. PubMed ID: 19768988.
    Abstract:
    A series of aaptamines, including one new alkaloid (1), were isolated from the marine sponge Aaptos sp. collected in Vietnamese waters. The structure of 1 was elucidated using NMR and HRESIMS, as well as by chemical transformation of 1 to the previously known aaptamine and established as 3-N-morpholinyl-9-demethyl(oxy)aaptamine. The isolated compounds showed a potential cancer preventive activity.
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