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  • Title: Disease progression in HIV-1-infected patients heterozygous for the sickle hemoglobin gene.
    Author: Sellier P, Masson E, Zini JM, Simoneau G, Magnier JD, Evans J, Bergmann JF.
    Journal: AIDS; 2009 Nov 13; 23(17):2362-4. PubMed ID: 19773632.
    Abstract:
    The sickle cell trait-asymptomatic carriage is frequent in people originating from sub-Saharan Africa. Several host factors (including sickle cell anemia) have been previously reported to act upon the course of HIV disease. We studied the progression of infection in a cohort of African patients heterozygous for the sickle hemoglobin gene and harboring normal hemoglobin genes. No significant difference was evidenced between the two groups from this preliminary study.
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