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  • Title: Air-stable secondary phosphine oxide as preligand for palladium-catalyzed intramolecular alpha-arylations with chloroarenes.
    Author: Ackermann L, Vicente R, Hofmann N.
    Journal: Org Lett; 2009 Oct 01; 11(19):4274-6. PubMed ID: 19775182.
    Abstract:
    A palladium catalyst derived from air-stable secondary phosphine oxide (1-Ad)(2)P(O)H enabled efficient intramolecular alpha-arylations of amides with aryl chlorides, which allowed for the synthesis of diversely substituted (aza)oxindoles.
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