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  • Title: Combined inheritance of epithelial and erythrocyte receptors for Haemophilus influenzae.
    Author: van Alphen L, Levene C, Geelen-van den Broek L, Poole J, Bennett M, Dankert J.
    Journal: Infect Immun; 1990 Nov; 58(11):3807-9. PubMed ID: 1977707.
    Abstract:
    Haemophilus influenzae type b expressing fimbriae showed no adherence to buccal epithelial cells and no agglutination of erythrocytes from three AnWj-negative siblings in one family. Hemagglutination of erythrocytes from 13 AnWj-positive members of the same family and from 24 controls was normal, and H. influenzae adhered well to buccal epithelial cells from them. These data indicate that the expression of epithelial and erythrocyte receptors for H. influenzae is inherited concomitantly. Combined with previous data (L. van Alphen, J. Poole, L. Geelen, and H. Zanen, Infect. Immun. 55:2355-2358, 1987), the results show that the receptor molecules on the surfaces of the epithelial cell and the erythrocyte are different but that the binding sites for the fimbriae of H. influenzae are similar.
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