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  • Title: [Methotrexate: safe if prescribed correctly].
    Author: Verduijn MM, van den Bemt BJ, Dijkmans BA, van der Waal RI, Horikx A.
    Journal: Ned Tijdschr Geneeskd; 2009; 153():A695. PubMed ID: 19785857.
    Abstract:
    Methotrexate (MTX) is an effective medicine that can be safely used for the treatment of rheumatic arthritis and severe cases of psoriasis. For nearly all indications MTX is prescribed as a weekly dose. As a result of prescription errors, miscommunication, failing pharmacovigilance and lack of knowledge, fatal incidents have occurred due to prescriptions for a dosage once daily instead of once weekly. To prevent such incidences in the future, a balanced automatic pharmacovigilance, clear instructions for the use of MTX on the prescription and good patient information are needed.
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