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  • Title: Colorimetric detection of thiols using a chromene molecule.
    Author: Huo FJ, Sun YQ, Su J, Chao JB, Zhi HJ, Yin CX.
    Journal: Org Lett; 2009 Nov 05; 11(21):4918-21. PubMed ID: 19788282.
    Abstract:
    A new thiol-containing colorimetric probe has been developed by using a chromene derivative, 7-nitro-2,3-dihydro-1H-cyclopenta[b]chromen-1-one (1). The molecule exhibited high selectivity and sensitivity for detecting thiol species as cysteine, homocysteine, and glutathione in aqueous solution through a rapid visual color change from colorless to yellow.
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