These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Heat-induced structural transition of alpha-crystallin in the eye lens tissue observed by small-angle X-ray scattering].
    Author: Krivandin AV.
    Journal: Biofizika; 2009; 54(4):638-40. PubMed ID: 19795784.
    Abstract:
    Heat-induced structural transitions of crystallins in the eye lens tissue have been studied by small-angle X-ray scattering. It was shown that a short-time (approximately 1 min) incubation of the bovine eye lens tissue at a temperature of about 60 degrees C leads to a pronounced shift of the small-angle X-ray diffraction maximum due to the short-range order of alpha-crystallin oligomers. This shift indicates an increase in the molecular mass of alpha-crystallin oligomers. The results are evidence that, in the native surrounding and at the native concentration of alpha-crystallin, heat-induced transition of alpha-crystallin quaternary structure takes place. Earlier, this transition of alpha-crystallin has been observed only in solutions and gels of this protein. The results confirm the identity of alpha-crystallin properties in vitro and in vivo.
    [Abstract] [Full Text] [Related] [New Search]