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  • Title: Embryonic vs. adult myogenesis: challenging the 'regeneration recapitulates development' paradigm.
    Author: Wang J, Conboy I.
    Journal: J Mol Cell Biol; 2010 Feb; 2(1):1-4. PubMed ID: 19797316.
    Abstract:
    A popular theory in the stem cell field is that 'regeneration recapitulates development', or that adult stem cells function similarly to embryonic ones. In a recent Nature article, Lepper et al. questioned this approach, highlighting the differences in requirements for Pax7 during myogenesis for embryonic, juvenile and adult muscle.
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