These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Enantioselective synthesis of 1,2,3-trisubstituted cyclopropanes using gem-dizinc reagents.
    Author: Zimmer LE, Charette AB.
    Journal: J Am Chem Soc; 2009 Nov 04; 131(43):15624-6. PubMed ID: 19813709.
    Abstract:
    The first asymmetric cyclopropanation of allylic alcohols using gem-dizinc carbenoids, which allows the synthesis of 1,2,3-substituted cyclopropane derivatives in high yields and excellent enantio- and diastereoselectivities, is reported. The initially formed cyclopropylzinc undergoes an in situ B/Zn exchange with the stoichiometric chiral ligand to generate a cyclopropyl borinate that can be directly engaged in a Suzuki-Miyaura cross-coupling reaction.
    [Abstract] [Full Text] [Related] [New Search]