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  • Title: [Peripheral blood T-cell subsets in patients with ovarian malignancies].
    Author: Liang LZ.
    Journal: Zhonghua Zhong Liu Za Zhi; 1990 Nov; 12(6):410-3. PubMed ID: 1981699.
    Abstract:
    Blood samples from 79 subjects (27 cases of ovarian malignancy, 2 ovarian borderline epithelial tumor, 38 benign gynecologic disease and 12 healthy women) were measured for peripheral blood T-cell subsets using monoclonal antibodies and SPA-Ig rosette technique. It was found that in patients with ovarian malignancy, the percentage of OKT4+ cells was significantly reduced whereas the percentage of OKT8+ cells was markedly increased as compared with those in the healthy women and patients with benign gynecologic disease; OKT4/OKT8 ratio declined obviously; which were more pronounced in patients with advanced or recurrent tumor.
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