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  • Title: Antibiotics for community-acquired pneumonia.
    Author: Dryden M, Hand K, Davey P, BSAC Council.
    Journal: J Antimicrob Chemother; 2009 Dec; 64(6):1123-5. PubMed ID: 19820250.
    Abstract:
    Antibiotic guidelines for community-acquired pneumonia (CAP) often recommend broad-spectrum agents for severe pneumonia. While these may be entirely appropriate in terms of their spectrum of activity and efficacy, there is a risk that such recommendations could result in over-prescribing of broad-spectrum agents with consequent 'collateral damage', meaning superinfection by resistant pathogens, or selection of antibiotic resistance. Narrow-spectrum agents are often as effective and result in less collateral damage. National and local antibiotic guidance should promote choices of agents for narrow-spectrum prescribing even for severe CAP where appropriate.
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