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  • Title: An efficient method for the preparation of peptide alcohols.
    Author: Katritzky AR, Abo-Dya NE, Tala SR, Gyanda K, Abdel-Samii ZK.
    Journal: Org Biomol Chem; 2009 Nov 07; 7(21):4444-7. PubMed ID: 19830293.
    Abstract:
    N-protected LL-dipeptide alcohols 3a-p, diastereomeric mixture (3d + 3d') and tripeptide alcohols 6a-c were synthesized by treatment of various amino alcohols with N-protected(alpha-aminoacyl)benzotriazoles 1a-c, 1f-m, (1a + 1a') and N-protected(alpha-dipeptidoyl)benzotriazoles 5a, 5b respectively in good yields with complete retention of chirality.
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