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Title: Is antigen specificity of autoreactive T cells the key to islet entry? Author: Penaranda C, Bluestone JA. Journal: Immunity; 2009 Oct 16; 31(4):534-6. PubMed ID: 19833083. Abstract: It has been widely hypothesized that pancreatic islet infiltrates include both islet-antigen-specific and nonspecific T cells. In this issue of Immunity, Lennon et al. (2009) demonstrate that islet-antigen specificity is required for accumulation in the islets.[Abstract] [Full Text] [Related] [New Search]