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  • Title: Pioglitazone induced reversible pancytopenia.
    Author: Karakurt F, Kargili A, Kasapoglu B.
    Journal: Exp Clin Endocrinol Diabetes; 2010 Feb; 118(2):96-7. PubMed ID: 19834871.
    Abstract:
    Pioglitazone is used to improve insulin sensitivity in type 2 diabetes. This group of drugs is usually well tolerated; however, their use may be associated with several adverse effects including edema, weight gain, macular edema and heart failure. Herein we report a patient who developed pancytopenia on the 7th day of oral pioglitazone treatment for the control of diabetes mellitus and fully recovered 6 days after the cessation of this drug. To the best of our knowledge this is the first reported case of pancytopenia induced by pioglitazone therapy.
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