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  • Title: [Value of intraoperative lysis therapy as an adjuvant measure after late surgical embolectomy].
    Author: Boos C, Hohlbach G, Reusche E, Richter P.
    Journal: Langenbecks Arch Chir Suppl II Verh Dtsch Ges Chir; 1990; ():435-6. PubMed ID: 1983585.
    Abstract:
    The effect of intraoperative local fibrinolysis after delayed catheterembolectomy (CE) of occluded arteries was examined in a model in the dogs hind limb; the superficial femoral artery was occluded by a rapid injection of an autologeous blood clot and ligation. Embolectomy was performed 24 h after occlusion with or without additional local fibrinolysis (urocinase, r-tPA). The success of revascularisation was estimated by measurement of the total periphereal resistance. There happened a total re-occlusion in all vessels within 48 h if only CE was performed; in contrast after additional fibrinolysis a complete revascularisation could be achieved.
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