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  • Title: A novel fluorescent and chromogenic probe for cyanide detection in water based on the nucleophilic addition of cyanide to imine group.
    Author: Sun Y, Liu Y, Chen M, Guo W.
    Journal: Talanta; 2009 Dec 15; 80(2):996-1000. PubMed ID: 19836585.
    Abstract:
    A fluorescent and colorimetric probe bearing salicylaldehyde hydrazone functionality has been prepared for cyanide sensing. The detection of cyanide was performed via the nucleophilic attack of cyanide anion on the imine group of the probe with a 1:1 binding stoichiometry, which could be confirmed by (1)H NMR and MS studies. The specific reaction results in a prominent fluorescence enhancement and a color change from colorless to yellow.
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