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  • Title: 1,5-diazacyclohenicosane, a new cytotoxic metabolite from the marine sponge Mycale sp.
    Author: Coello L, Martín MJ, Reyes F.
    Journal: Mar Drugs; 2009 Sep 15; 7(3):445-50. PubMed ID: 19841724.
    Abstract:
    A new cyclic diamine, 1,5-diazacyclohenicosane (1), was isolated from samples of the marine sponge Mycale sp. collected at Lamu Island (Kenya). Its structure was determined by a combination of spectroscopic techniques, including (+)-HRESIMS and 1D and 2D NMR spectroscopy. The compound displayed cytotoxicity at the muM level against three human tumor cell lines.
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