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  • Title: Decussation of bulbospinal respiratory axons at the level of the phrenic nuclei in adult rats: a possible substrate for the crossed phrenic phenomenon.
    Author: Goshgarian HG, Ellenberger HH, Feldman JL.
    Journal: Exp Neurol; 1991 Jan; 111(1):135-9. PubMed ID: 1984430.
    Abstract:
    The axonal trajectories of inspiratory bulbospinal neurons were examined after deposition of the anterograde neuronal tracer phaseolus vulgaris leucoagglutinin (PHA-L) into the rostral ventral respiratory group in rats. At the level of the phrenic nucleus, PHA-L-labeled bulbospinal axons crossed the midline of the spinal cord in both the anterior gray and the anterior white commissure. These spinally decussating neurons provide a possible anatomical substrate for the respiratory reflex known as the crossed phrenic phenomenon.
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