These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Dietary intake and plasma concentrations of PUFA and LC-PUFA in breastfed and formula fed infants under real-life conditions.
    Author: Schwartz J, Drossard C, Dube K, Kannenberg F, Kunz C, Kalhoff H, Kersting M.
    Journal: Eur J Nutr; 2010 Apr; 49(3):189-95. PubMed ID: 19851802.
    Abstract:
    BACKGROUND: The breastfed infant is usually used as standard for formula feeding, also regarding long-chain polyunsaturated fatty acids (LC-PUFA). Here, plasma fatty acid concentrations in formula fed infants and the effects of LC-PUFA supplementation were investigated under real-life conditions. METHOD: Term healthy infants being fully milk fed until the age of 4 months were categorized as breast milk "BM" (n = 73) if consuming >95% of energy from breast milk or formula (F) if consuming >95% of energy from formula subdivided into formula without (F-) (n = 15) and with LC-PUFA supplementation (F+) (n = 15). Formula as marketed was chosen by the parents. Dietary fatty acids (FA) intake was calculated from continuous dietary records from 2 months of age onwards. Total plasma FA were analyzed at the age of 4 months with docosahexaenoic acid (DHA) as primary outcome. RESULTS: Dietary ratios of the polyunsaturated fatty acids (PUFA; linoleic acid/alpha-linolenic acid) were smaller in both F groups than in the BM group. Plasma DHA as % of total FA was similar in BM and F(+) but higher in BM in absolute amounts (mg/L). Plasma DHA as % of total FA in F(-) was higher than what might be supposed on the basis of dietary intake. CONCLUSION: Infants consuming present-day LC-PUFA-supplemented formula achieved plasma LC-PUFA concentrations similar to breastfed infants. In infants consuming non-LC-PUFA-supplemented formula, the favorable PUFA pattern of the formula may have supported n-3 LC-PUFA biosynthesis.
    [Abstract] [Full Text] [Related] [New Search]