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  • Title: Passive nonlinear elastic behaviour of skeletal muscle: experimental results and model formulation.
    Author: Calvo B, Ramírez A, Alonso A, Grasa J, Soteras F, Osta R, Muñoz MJ.
    Journal: J Biomech; 2010 Jan 19; 43(2):318-25. PubMed ID: 19857866.
    Abstract:
    The goal of this study was to characterize the passive elastic behaviour of muscle and tendon tissues of rat tibialis anterior. For that purpose, tissue samples from 3 month old female Wistar rats (210+/-11g) were mechanically tested in vitro. Moreover, an in vivo device was developed to measure the muscle-tendon unit response to increasing load. Mechanical tests, consisting of uniaxial loading along the longitudinal axis of tendon and muscle strips, revealed the nonlinear mechanical behaviour of these tissues. A material model was formulated and its parameters fit to the experimental data using the Levenberg-Marquardt optimization algorithm. The fit goodness was assessed and R(2) values close to 1 and very low epsilon values were obtained. The passive behaviour of a future finite element model of a muscle-tendon unit will be validated against the in vivo passive extension tests by comparing the reaction force-extension curves.
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