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  • Title: Efficient synthesis of 3-arylphthalides using palladium-catalyzed arylation of aldehydes with organoboronic acids.
    Author: Kuriyama M, Ishiyama N, Shimazawa R, Shirai R, Onomura O.
    Journal: J Org Chem; 2009 Dec 04; 74(23):9210-3. PubMed ID: 19873994.
    Abstract:
    The synthesis of 3-arylphthalides via palladium-catalyzed arylation of aldehydes with organoboronic acids was achieved using the thioether-imidazolinium carbene ligand in good to excellent yields and was carried out using 1.0 mol % of the catalyst with high substrate tolerance.
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