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  • Title: Larvicidal effects of the major essential oil of Pittosporum tobira against Aedes aegypti (L.).
    Author: Chung IM, Seo SH, Kang EY, Park WH, Moon HI.
    Journal: J Enzyme Inhib Med Chem; 2010 Jun; 25(3):391-3. PubMed ID: 19874194.
    Abstract:
    Essential oil obtained from the leaves of Pittosporum tobira was extracted and its chemical composition and larvicidal effects were studied. Analyses were conducted by gas chromatography and mass spectroscopy (GC-MS) to determine the primary constituents of the essential oil of P. tobira. The yield of P. tobira essential oil (PTEO) was 0.1%, and GC-MS analysis identified its major constituents as undecane (31.11%), 4-methyl-1,3-pentadiene (11.34%), (1,3-dimethyl-2-butenyl)benzene (5.45%), and L-limonene (14.08%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti (L.), with an LC(50) value of 58.92 ppm and an LC(90) value of 111.31 ppm. Finally, the LC(50) and LC(90) values of L-limonene were 39.7 ppm and 78.11 ppm. These results could be useful for seeking newer, safer, and more effective natural larvicidal agents against A. aegypti.
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