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  • Title: Radiation-induced spindle cell sarcoma: a rare case report.
    Author: Khan M, Chandramala R, Sharma R, Vijayalakshmi KR.
    Journal: Indian J Dent Res; 2009; 20(3):380-4. PubMed ID: 19884729.
    Abstract:
    Ionizing radiation has been known to induce malignant transformation in human beings. Radiation-induced sarcomas are a late sequel of radiation therapy. Most sarcomas have been reported to occur after exposure to a radiation dose of 55 Gray (Gy) and above, with a dose ranging from 16 to 112 Gys. Spindle cell sarcomas, arising after radiotherapy given to treat the carcinoma of head and neck region is a very uncommon sequel. This is a rare case report of spindle cell sarcoma of left maxilla, in a 24-year-old male, occurring as a late complication of radiotherapy with Cobalt-60 given for the treatment of retinoblastoma of the left eye 21 years back.
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