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  • Title: Abrupt emergence of long-lasting memory in the pre-weanling rat.
    Author: Languille S, Richer P, Hars B.
    Journal: Behav Brain Res; 2010 Mar 05; 207(2):515-9. PubMed ID: 19891993.
    Abstract:
    During the course of ontogenesis does long-lasting memory emerge progressively or abruptly, and when? To examine this question, rat pups were conditioned at different ages (3-, 10-, 12-, 15- or 18-day-old) and tested at different retention intervals: from 3 days to 1 year. Conditioned aversion memory established before 12-day-old lasts for only 1 week, but when acquired after 15 days, memory survives for more than 1 year. This defines a short temporal window of 3 days for sudden emergence of a remote memory. Our result offers a precise temporal target to explore the mechanisms involved in long maintenance of memory.
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