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  • Title: Single HCC between 2 and 5 cm: the grey zone: hepatologist's perspective.
    Author: Kudo M, Chung H.
    Journal: J Hepatobiliary Pancreat Sci; 2010 Jul; 17(4):434-7. PubMed ID: 19902137.
    Abstract:
    Long term survival of single nodular hepatocellular carcinoma (HCC) measuring 2-5 cm in size treated with radiofrequency ablation (RFA) was compared between 157 HCCs treated with RFA and 89 HCCs treated by operation. The 5 year survival rate was not significantly different between RFA and operation. In addition, the 17th nationwide survey of the Liver Cancer Study Group of Japan clearly showed that 5 year survival rate in 858 HCCs measuring 2-5 cm in size treated with RFA was similar to that in 6,574 HCCs measuring 2-5 cm in size treated by operation. In conclusion, RFA achieves outcomes similar to those of operation for Child-Pugh A patients with HCCs measuring 2-5 cm in size.
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