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  • Title: Multicentric Castleman's disease & HIV infection.
    Author: Cotter A, Lambert J, O'Gorman P.
    Journal: Ir Med J; 2009 Oct; 102(9):294-5. PubMed ID: 19902650.
    Abstract:
    We report the case of a 35 year patient from Nigeria who presented with fever and splenomegaly. The initial diagnosis was Salmonellosis. However, relapsing symptoms lead to a re-evaluation and ultimately a diagnosis of Multicentric Castleman's Disease (MCD). There is no gold standard treatment but our patient responded to Rituximab and Highly active anti-retroviral therapy. MCD is a rare, aggressive disease that should be considered in a HIV positive patient presenting with fever and significant lymphadenopathy.
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