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  • Title: Effective desensitization to imiglucerase in a patient with type I Gaucher disease.
    Author: Peroni DG, Pescollderungg L, Piacentini GL, Cassar W, Boner AL.
    Journal: J Pediatr; 2009 Dec; 155(6):940-1. PubMed ID: 19914435.
    Abstract:
    We describe a child who had anaphylactic hypersensitivity to imiglucerase therapy for Gaucher disease. Treatment was stopped and symptoms returned. After immune desensitization to imiglucerase using a rush protocol, the patient was able to resume treatment and has not had further hypersensitivity complications to date.
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