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  • Title: Genotoxicity of the fungicide dichlofluanid in seven assays.
    Author: Heil J, Reifferscheid G, Hellmich D, Hergenröder M, Zahn RK.
    Journal: Environ Mol Mutagen; 1991; 17(1):20-6. PubMed ID: 1991455.
    Abstract:
    Seven different endpoints for detection of genotoxicity have been used to demonstrate the DNA-altering properties of Dichlofluanid, a fungicide commonly used in viticulture pest control. Each endpoint (DNA synthesis inhibition test, alkaline viscosimetry, umu-test, alkaline filter elution, FADU-test, 32P-postlabeling, and electron microscopy) shows clear evidence of genotoxicity. These data indicate that application of the fungicide dichlofluanid may be mutagenic and/or carcinogenic for exposed humans.
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