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  • Title: [A new screening method for determining tolerant intraocular pressure].
    Author: Avetisov SE, Mamikonian VR, Kazarian EE, Shmeleva-Demir OA, Mazurova IuV, Ryzhkova EG, Galoian NS, Tatevosian AA.
    Journal: Vestn Oftalmol; 2009; 125(5):3-7. PubMed ID: 19916324.
    Abstract:
    The authors proposed a new screening for determining individual tolerant intraocular pressure (TIOP). The investigation covered 107 individuals (167 eyes). All the examinees were divided into three groups. Groups 1 and 3 comprised healthy volunteers without the signs of vascular changes and glaucoma; Group 2 included patients with new-onset glaucoma with uncompensated intraocular pressure (IOP). There was a regression relationship of ocular blood flow (OBF) to the length of the anteroposterior ocular axis (APOA), which showed a high correlation between OBF and APOA. To determine TIOP, the authors proposed the calculation formula: TIOP = P x K/K(n), where P is the tonometric IOP (mm Hg); K is the flowmetric value of OBF (microl/sec); K(n) is the individual normal OBF value (microl/sec) determined by the nomogram developed by the authors, by taking into account the value of APOA (mm). It is suggested that the eye has a certain buffer range of excessive tolerant pressure within which increased ophthalmotonus results in abnormal sequels. The patients with TIOP that is lower than the existing IOP in the absence of glaucoma symptoms should be classified as a risk-group.
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