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  • Title: The structure of the brain-specific rat aldolase C gene and its regional expression.
    Author: Mukai T, Yatsuki H, Masuko S, Arai Y, Joh K, Hori K.
    Journal: Biochem Biophys Res Commun; 1991 Jan 31; 174(2):1035-42. PubMed ID: 1993044.
    Abstract:
    The rat aldolase C gene was isolated from a rat genomic DNA library. This gene comprises 9 exons and spans 3590 base pairs. A single copy of the gene occurs per haploid rat genome. The initiation of transcription occurs at two different sites. The cellular localization of aldolase C mRNA was determined in the central nervous system along with aldolase A mRNA by in situ hybridization. The result indicates the predominant expression of this gene in Purkinje cells of the cerebellar cortex, where aldolase A mRNA was rather repressed.
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