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  • Title: Rotavirus infection in hospitalized children and estimates of disease burden in Kyrgyzstan, 2005-2007.
    Author: Flem ET, Kasymbekova KT, Vainio K, Gentsch J, Abdikarimov ST, Glass RI, Bresee JS.
    Journal: Vaccine; 2009 Nov 20; 27 Suppl 5():F35-9. PubMed ID: 19931716.
    Abstract:
    To estimate the rotavirus-associated burden in Kyrgyzstan, we conducted hospital surveillance among children <5 years old with diarrhoea during 2005-2007. Of 3756 children hospitalized with diarrhoea, 26% had rotavirus detected in stool samples by an enzyme immunoassay. The virus genotype G1P[8] was identified in 60% of 190 characterized samples from 2005 to 2006. The estimated risk for rotavirus hospitalization by age 5 years was 1 in 28 children. One quarter of all gastroenteritis hospitalizations in children <5 years old in Kyrgyzstan may be attributable to rotavirus. Rotavirus vaccination could be an important health intervention to reduce the burden of rotavirus gastroenteritis.
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