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  • Title: Hospital-based surveillance and molecular epidemiology of rotavirus infection in Taiwan, 2005-2007.
    Author: Wu FT, Liang SY, Tsao KC, Huang CG, Lin CY, Lin JS, Su CY, Eng HL, Yang JY, Chen PJ, Yang CF.
    Journal: Vaccine; 2009 Nov 20; 27 Suppl 5():F50-4. PubMed ID: 19931720.
    Abstract:
    To determine the distribution of rotavirus strains and facilitate vaccine policy decisions in Taiwan, active hospital-based gastroenteritis surveillance was conducted in three sentinel hospitals. From 1 January 2005 to 31 December 2007, a total of 3435 children less than 5 years old with gastroenteritis were enrolled. The presence of rotavirus was documented by enzyme immunoassay (EIA), and the G and P genotypes were determined by reverse transcription-polymerase chain reaction (RT-PCR) and sequencing methods. Results confirmed that 856 (25%) of these gastroenteritis admissions were EIA-positive for rotavirus and 448 (52%) of the rotavirus positive admissions were less than 2 years old. The most prevalent rotavirus genotypes were G1P[8] (40%), followed by strains G3P[8] (27%), and G9P[8] (17%). These data will help inform decisions as to whether rotavirus vaccine should be considered for inclusion into Taiwan's National Immunisation Programme.
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