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  • Title: Use of intravenous fluids in Hong Kong children hospitalised for diarrhoea and relationship to severity and aetiology.
    Author: Chow CM, Choi K, Nelson EA, Chan PK, Mast TC, DiStefano D, Tam JS, Bresee JS.
    Journal: Vaccine; 2009 Nov 20; 27 Suppl 5():F55-60. PubMed ID: 19931721.
    Abstract:
    This study assessed the clinical management and impact of diarrhoea aetiology (rotavirus positive/negative) and rotavirus genotype on diarrhoeal disease severity. Of 7391 diarrhoea admissions less than 5 years of age over a 2-year period, 80% of patients were tested for rotavirus, 87% were cultured for bacterial pathogens and 78% were assessed for both. Diarrhoeal severity scores were greatest in those children with mixed rotavirus and bacterial infections. Between 1.3 and 8.4% of infants were considered dehydrated yet intravenous fluids were used for 48% of infants (69% rotavirus positive, 72% mixed infection). These findings support the promotion of oral rehydration therapy over intravenous fluids.
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