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  • Title: [Squamous cell carcinoma on a pleomorphic adenoma with amyloid stroma of the palate].
    Author: Chaari C, Ellouze S, Chamli H, Krichen Makni S, Karray F, Sellami Boudawara T.
    Journal: Rev Stomatol Chir Maxillofac; 2010 Feb; 111(1):53-5. PubMed ID: 19932498.
    Abstract:
    INTRODUCTION: Squamous cell carcinoma ex-pleomorphic adenoma (CXAP) is a malignant and rare mixed tumor. We report a new case. OBSERVATION: A seventy-year-old woman consulted for a mass in the left hemi-face having evolved over the last 20years. The physical examination revealed a hard and large tumor invading all the palate. Computed tomography revealed a heterogeneous 8.5cm long maxillary mass. The diagnosis of CXAP was made on a biopsy. A histological study confirmed the diagnosis after surgical resection of the tumor, specifying its noninvasive character. DISCUSSION: CXAP is generally located in the parotid gland; it is very rarely located in the palate. The degenerated epithelial component generally corresponds to an adenocarcinoma or an undifferentiated carcinoma; squamous-cell carcinoma is more rarely reported. The prognosis is excellent for the micro and noninvasive types. Surgery remains the treatment of choice.
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