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  • Title: Acute mesenteric and aortic thrombosis associated with antithrombin deficiency: a rare occurrence.
    Author: Calcaterra D, Martin JT, Ferneini AM, De Natale RW.
    Journal: Ann Vasc Surg; 2010 Apr; 24(3):415.e5-7. PubMed ID: 19932950.
    Abstract:
    Antithrombin is a potent inhibitor of the coagulation cascade exerting its primary effects on activated factors X, IX and II. It is the mechanism by which heparin and low-molecular weight heparin cause anti-coagulation. Deficiency of antithrombin presents as a hypercoagulable state, and may result in unexplained deep venous thrombosis, arterial thrombosis and systemic embolization.
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