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  • Title: 8-azapurine nucleus: a versatile scaffold for different targets.
    Author: Giorgi I, Scartoni V.
    Journal: Mini Rev Med Chem; 2009 Oct; 9(12):1367-78. PubMed ID: 19939217.
    Abstract:
    -Azapurine nucleus is a bioisoster of the purine nucleus. Variously substituted 8-azapurines have been synthesised and studied for their interactions with many enzymes and receptors and for their antitumor and antiviral activity. In this paper the main results of the studies made in these last years on this topic are reported.
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