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  • Title: Adult T-cell leukemia-lymphoma associated with follicular mucinosis.
    Author: Wada T, Yoshinaga E, Oiso N, Kawara S, Kawada A, Kozuka T.
    Journal: J Dermatol; 2009 Dec; 36(12):638-42. PubMed ID: 19958447.
    Abstract:
    Follicular mucinosis (alopecia mucinosa) is often associated with malignancies including mycosis fungoides and Sézary syndrome, but not adult T-cell leukemia-lymphoma (ATLL). We report a 49-year-old male patient who had pruritic follicular papules and erythemas clinically, and follicular and perifollicular infiltrates and follicular mucin deposition histopathologically. The patient showed 11% of flower-shaped atypical lymphocytes in blood examination and positive human T-cell leukemia virus type 1 antibody in serology, consistent with the chronic type of ATLL. This case seems to be a very rare association of follicular mucinosis and chronic ATLL, suggesting that malignant T cells may have a feature of folliculotropism as well as epidermotropism.
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