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  • Title: [Selective pituitary resistance to thyroid hormone in a patient treated with amiodarone].
    Author: Gómez JJ, Pomar MD, Casariego AV, Rodríguez IC.
    Journal: Endocrinol Nutr; 2009 Oct; 56(8):418-21. PubMed ID: 19959152.
    Abstract:
    Selective pituitary resistance to thyroid hormones is a syndrome that involves inadequate response of thyroid-stimulating hormone to changes in thyroid hormones. Unlike generalized resistance syndromes, this entity produces central hyperthyroidism and clinical thyrotoxicosis. Sometimes the disease may not be properly diagnosed and is treated with drugs with harmful effects on the thyroid, such as amiodarone, hampering diagnosis and possibly exacerbating the disorder. The treatment of this condition can be symptomatic, based on control of tachycardia and anxiety, or etiological, acting on the pituitary to regulate thyrotropin secretion or on the thyroid gland to control thyroid hormone production. We report the case of a patient with pituitary resistance to thyroid hormone, who was treated with amiodarone to control paroxysmal atrial fibrillation.
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