These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Cytogenetic effect of small doses of tritium beta irradiation].
    Author: Stiazhkina TV, Gorbunova IN, Khaĭmovich TI.
    Journal: Med Radiol (Mosk); 1991; 36(1):33-5. PubMed ID: 1996052.
    Abstract:
    The effect of tritium beta-radiation within the dose range of 0.5 x 10(-3) = 0.6 Gy on human blood lymphocytes in vitro was investigated. Dose-effect correlation was determined by the frequency of aberrant cells and the sum of chromosome aberrations per 100 cells. As compared to a rated curve corresponding to a linear-quadratic model y = a + bD + cD2, experimental curves (showing correlation between cytogenetic indices and a dose) are of abnormal nature with a plateau in a dose range less than 7.5 x 10(-2) Gy. A big confidence interval of cytogenetic effect indices in a dose range less than 7.5 x 10(-2) Gy was shown to be determined by the number of analyzed metaphases. The proof of significance of a plateau on a dose-effect curve in regions of small doses (e.g. with a confidence interval of +/- 24%) necessitated analysis of no less than 10,000 metaphases per dose.
    [Abstract] [Full Text] [Related] [New Search]