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  • Title: Selective micro preconcentration of propofol for anesthetic depth monitoring by using seedless electroplated gold as adsorbent.
    Author: Alfeeli B, Zareian-Jahromi MA, Agah M.
    Journal: Annu Int Conf IEEE Eng Med Biol Soc; 2009; 2009():2763-6. PubMed ID: 19964594.
    Abstract:
    This communication presents selective preconcentration of the anesthetic agent (Propofol) and the elimination of unwanted species from a representative sample of human breath. In this approach, a micro preconcentrator (microPC) consisting of embedded high-aspect-ratio pillars (30 microm x 120 microm chi 240 microm), an outer dimensions of 7 mm x 7 mm (encompass more than 3500 micro pillars), total inner surface area of approximately 10 m(2), and a total inner volume of approximately 6.5 microL was used to selectively preconcentrate Propofol. The microPC has on-chip thermal desorption capability and was coated by electrodeposited gold as an adsorbent material. Experimental evaluations showed successful preconcentration of trace level of Propofol from a mixture containing several volatile organic compounds diluted in water-like solvent (1-propanol) and the efficient removal of non-polar compounds present in the mixture.
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