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  • Title: Apparent response of subacute sclerosing panencephalitis to intrathecal interferon alpha.
    Author: Miyazaki M, Hashimoto T, Fujino K, Goda T, Tayama M, Kuroda Y.
    Journal: Ann Neurol; 1991 Jan; 29(1):97-9. PubMed ID: 1996885.
    Abstract:
    An 8-year-old boy with subacute sclerosing panencephalitis (SSPE) was treated with 1.0 to 3.0 x 10(6) IU human interferon alpha (IFN) by the intrathecal route weekly or fortnightly. Pronounced improvement of clinical and electroencephalographic findings were observed in a dose-dependent manner. Our patient raises hope that IFN can induce sustained remission in patients with SSPE.
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