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  • Title: [Small cell lung cancer complicated by opsoclonus myoclonus syndrome].
    Author: Iwata T, Yokomura I, Ohsugi S, Uesaka A, Sekiguchi K, Nishio A.
    Journal: Nihon Kokyuki Gakkai Zasshi; 2009 Nov; 47(11):1046-50. PubMed ID: 19994603.
    Abstract:
    Opsoclonus myoclonus syndrome, one of the paraneoplastic neurological syndromes involving several neurological symptoms that result from "remote effects" of cancer, is a rare disease characterized by opsoclonus, cerebellar ataxia and myoclonus of the trunk and extremities. A 53-year-old man was admitted with dizziness and difficulty walking. Medical examinations led to a diagnosis of opsoclonus myoclonus syndrome. CT scans showed mediastinal and cervical lymphadenopathy, and a diagnosis of small cell lung cancer was made. Steroid therapy and chemotherapy (carboplatin + etoposide) produced significant improvement in the neurological symptoms.
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